Master of Chemical & Life Sciences

MCLFS Instructors

Alaghmand | Bottino | Boehlmer | Bottrell | Brooks | English | Hall | Higgins | Jack | Jarvis | Jollie | Kapp | Kent | D. Mazzocchi | P. Mazzocchi | Norcross | Pontzer | O’Brien | Trun

Marjan Alaghmand, Ph.D.

Dr. Alaghmand received her Ph.D. from University of Maryland, College Park in chemistry. She was a postdoctoral research associate at chemistry department, Purdue University. During her postdoctoral research, she collaborated with numbers of scientists at University of Michigan Ann Arbor, Indiana University, University of Wisconsin Madison and State University of New York. After her post doctoral research, she worked as a scientist in pharmaceutical industry. Dr. Alaghmand is currently one of the faculty members at George Mason University. Her research interests and activities include cancer therapy, immunotherapy, cancer diagnosis, toxicology, climate change, water and air pollutions and their health and environmental impacts. She is a member of American Chemical Society (ACS) and American Association for Advancement of Science (AAAS). She has published several peer-reviewed journal papers and presented in various international conferences.

Postdoctoral Research Fellowship, Department of Chemistry, Purdue University, 2009
Ph.D. Analytical Chemistry, University of Maryland, College Park, 2007
M.S. Analytical Chemistry, Shahid Beheshti (Melli) University, 1999
B.S. Applied Chemistry, Sharif University of Technology, 1996     

1st place, physical science research award, 2017
Awards Research and Technology Award, Ministry of Science, Research and Technology, 2000
Dean's Honored Graduate, Shahid Beheshti (Melli) University, 1999
Dean's Honored Graduate, Sharif University of Technology, 1996

Professional Experiences
Assistant Professor, George Mason University, Department of Chemistry & Biochemistry, 2012-present
Adjunct Faculty, Northern Virginia Community College, 2012-2013
Adjunct Faculty, Montgomery College, 2011-2012
Scientist, Panacea Pharmaceuticals Inc., 2009-2013
Postdoctoral research associate, Purdue University, 2007-2009
Laboratory Chief, Niroo Research Institute, Energy and Environment Research Center, 2000-2001
Instructor, Azad University, Department of Chemistry, 1996-2001

Selected Publications
M. Alaghmand, P. B. Shepson, T. K. Starn, B. T. Jobson, et al., “The Morning NOx Maximum in the Clean Air Forest Boundary Layer.” Submitted to Atmospheric chemistry and Physics.
S. M. Griffith, R. F. Hansen, S. Dusanter, P. S. Stevens, M. Alaghmand, P. B. Shepson, et al. “OH and HO2 Radical Chemistry during PROPHET 2008 and CABINEX 2009 - Part 1: Measurements and Model Comparison.” Atmospheric chemistry and Physics (2013) 13, 5403-5423.
K. A. Pratt, L. Milekie, P. B. Shepson, M. A. Carroll, M. Alaghmand, et al., “A one-dimensional model study of individual reactive biogenic volatile organic compounds and their contributions to organic nitrates above a mixed forest” Atmospheric chemistry and Physics (2012) 12, 10125-10143.
X. Zhou, N. Zhang, S. Bertman, M. Alaghmand, P.B. Shepson, et al. “Nitric acid photolysis on forest canopy surface as a source for tropospheric nitrous acid.” Nature Geoscience (2011) 4, 440-443.

Paul Bottino, Ph.D.

1964 BS Utah State University - Biology/Secondary Education
1964: MS Utah State University - Botany/Cytogenetics
1969: PhD Washington State University-Genetics
1969-73: Brookhaven National Laboratory - Research Associate
1973: Assistant Professor University of Maryland
1976: Associate Professor University of Maryland
July 1988 - January 1989: Visiting Scientist, Dept. Microbiology, University of Washington
1990-1997: Associate Chair Department of Plant Biology
July 2003: Retired University of Maryland

Research Interests
Plant Transformation and Plant Molecular Genetics. Interested in two classes of plant genes. Receptor Protein Kinases, and Plant Cellulases. We first clone various genes from these two classes, use RNAi approaches to determine each gene's function. Then we used transgenic plants with reporter genes to reveal the site and timing of expression of each of these genes.
In retirement, he lives near the beach in southern Delaware, and teaches MLFSC 620-Modern Molecular Genetics. Hobbies include an outdoor model railroad, ATV riding, surf fishing, beach bumming, and traveling.

Debra Boehlmer, Ph.D.

Deb Boehmler is passionate about chemistry and loves to challenge and excite students in this field. Her research focused on organic synthesis, primarily studying stereo-selective reactions and the total synthesis of biologically active natural products. As a lecturer at the University of Maryland, she taught both general and organic chemistry to a wonderfully motivated and talented group of undergraduates. During this time, she helped develop new teaching innovations in the department, such as on-line assessment and student response systems (clickers). She is thrilled to continue engaging students in the MCLFS program.

1997 B.S. Chemistry with Honors
DePaul University, Chicago, IL
1999 M.S. Chemistry
University of Rochester, NY
2002 Ph.D. Chemistry
University of Rochester, NY
Research Advisor: Prof. Robert K. Boeckman, Jr.
(Dissertation: I. Alkylations of acylated camphor-derived chiral auxiliaries including those containing an a-oxygen; II. Studies toward the total synthesis of rasfonin.)
2006 Chemistry 737: "Chemical Education Research: Theory and Practice."
Catholic University of America, Washington, DC

Postdoctoral Research
2002-2003 Postdoctoral Fellow, Department of Chemistry & Biochemistry, University of Maryland, College Park, MD
Advisor: Prof. Philip DeShong
(Studies toward the synthesis of pancratistatin)

Professional Experience
2003-2007 Lecturer, Department of Chemistry and Biochemistry, University of Maryland, College Park, MD

Awards and Honors
2006: Robert Rowan Memorial Award for departmental service
2006: Distinguished Member - National Society of Collegiate Scholars
2006: Faculty Mentor – Merrill Presidential Scholars Program

Dale. G. Bottrell, Ph.D.

Research Interests
Current research is examining the potential of augmenting natural enemies by crop variety selection and modification. I am focusing on how intraspecific variation in corn (Zea mays) and chile peppers (Capsicum spp.) affects the attraction, fitness, and effectiveness of predators of lepidopteran pests. Work on corn is determining if pollen of different corn varieties varies in its effects on omnivorous predators. Work on Capsicum spp. is determining if the capsaicinoids in chile peppers mediate predation and if variation in the concentration of capsaicinoids across Capsicum varieties explains varietal difference in insect herbivory and biological control.
I am also interested in the broad issues of biodiversity and conservation biology, especially in the tropics. I have participated in the development of environmental assessments for the U. S. Agency for International Development in more than 25 developing countries of the tropics and served as team leader for one comprehensive Environmental Impact Statement (required by the National Environmental Policy Act) in the United States.

B.S. degree, Entomology, Oklahoma State University, 1963
Ph.D. degree, Entomology, Oklahoma State University, 1968

Representative Publications
Mathews CR, Bottrell DG, Brown MW. 2004. Habitat manipulation of the apple orchard floor to increase ground-dwelling predators and predation of Cydia pomonella (L.) (Lepidoptera: Tortricidae) Biological Control 30:265-73
Mathews CR, Bottrell DG, Brown MW. 2002. A comparison of conventional and alternative understory management practices for apple production: multi-trophic effects. Applied Soil Ecology 21:221-31
Ehler LE, Bottrell DG. 2000. The illusion of integrated pest management. National Academy of Sciences, Issues in Science and Technology XVI (3):61-63
Theunis W, Aguda RM, Cruz WT, Decock C, Peferoen M, Lambert B, Bottrell DG, Gould FL, Litsinger JA, Cohen MB. 1998. Bacillus thuringiensis isolates from the Philippines: habitat distribution, d-endotoxin diversity, and toxicity to rice stem borers (Lepidoptera: Pyralidae). Bulletin of Entomological Research 88:335-42
Schoenly KG, Justo HD Jr, Barrion AT, Harris MK, Bottrell DG. 1998. Analysis of invertebrate biodiversity in a Philippine farmer's irrigated rice field. Environmental Entomology 27:1125-36
Bottrell DG, Barbosa P, Gould F. 1998. Manipulating natural enemies by plant variety selection and modification: a realistic strategy? Annual Review of Entomology 43:347-367
Bottrell DG. 1996. The research challenge for integrated pest management in developing countries: a perspective for rice in Southeast Asia. Journal of Agricultural Entomology 13:185-193
Rapusas HR, Bottrell DG, Coll M. 1996. Intraspecific variation in the chemical attractiveness of rice to insect predators. Biological Control 6:394-400
Coll M, Bottrell DG. 1996. Movement of an insect parasitoid in simple and diverse plant assemblages. Ecological Entomology 21:141-149
Coll M, Bottrell DG. 1995. Predator-prey association in mono- and dicultures: effect of maize and bean vegetation. Agriculture, Ecosystems and Environment 54:115-125
Bottrell DG, Weil RR. 1995. Protecting crops and the environment: striving for durability, pp. 55-73. In Juo SR, Freed RD eds., Agriculture and Environment: Bridging Food Production and Environmental Protection in Developing Countries. ASA Special Publication No. 60. American Society of Agronomy, Crop Science Society of America, Soil Science Society of America, Madison, WI
Demayo CG, Gould FL, Bottrell DG, Romena AM, Angeles AT. 1994. Geographic variation in larval survival and growth of five Scirpophaga incertalus (Lepidoptera: Pyralidae) strains on different rice hosts. Environmental Entomology 23:1428-1435
Coll M, Bottrell DG. 1994. Effects of nonhost plants on an insect herbivore. Ecology 75:723-731

Awards and Recognition
Fellow of the Entomological Society of America (elected in 2004)
University of Maryland Distinguished International Service Award, 2004
College of Life Sciences Faculty Excellence Award for Teaching and Course Development, University of Maryland, 2003
Vietnamese Student Association Certification of Appreciation in Recognition of Outstanding Faculty Advisor, University of Maryland, 2001-2002
Rockefeller Foundation Bellagio Resident, 1997
Visiting Professor, University of the Philippines, Los Banos, Philippines, 1991-1993

HONR 208V Biodiversity on the Decline: Society's Biggest Threat
BSCI 120 Insects
BSCI 328D Biodiversity and Conservation Biology Laboratory
BSCI 366 Biodiversity Issues in Conservation Management
CLFS 660 Biodiversity and Conservation Biology

Michelle Brooks, Ph.D.

Michelle Mac Brooks is currently the Associate Director of the Biological Sciences Graduate Program at Maryland and is excited to reenter the realm of teaching. She was an assistant professor at the College of Charleston, where she taught courses in general chemistry, thermodynamics, and quantum mechanics and introduced guided scientific writing exercises into both the general and physical chemistry lab courses. In 2007 she moved to the University of Maryland as a lecturer where she helped develop a bioanalytical chemistry lab course that included an interdisciplinary module on bionanotechnology. She is looking forward to bringing her love of teaching and the world of chemistry to her MCLFS students.

1990 B.S. Biochemistry
Eastern Michigan University, Ypsilanti, MI
1998 Ph.D. Chemistry
Michigan State University, E.Lansing, MI
Research Advisors: Prof. Jerry Babcock and Prof. John McCracken
(Dissertation: Advanced Electron Magnetic Resonance Studies of Nitrogen Ligation in Photosynthetic Systems)

Postdoctoral Research
1996-1998 Postdoctoral Fellow, Department of Chemistry, Columbia University, New York, NY
Advisor: Prof. Ann McDermott
(Solid state NMR studies of chemically induced dynamic nuclear polarization in photosynthesis)

Professional Experience
1998-2000, Assistant Professor, Department of Natural Sciences, Lakeland College, Sheboygan, WI
2000-2007, Assistant Professor, Department of Chemistry and Biochemistry, College of Charleston, Charleston, SC
2000-2007, Lecturer, Department of Chemistry and Biochemistry, University of Maryland, College Park, MD
2000-2007, Associate Director, Biological Sciences Graduate Program, College of Computer, Mathematical, and Natural Sciences, University of Maryland, College Park, MD

Awards and Honors
1996: National Research Service Award, National Institutes of Health
2001: National Institutes of Health BRIN Program Award (co-investigator)
2008: Lilly Teaching Fellow, University of Maryland, College Park, MD
2009: HHMI Curriculum Redesign Award, University of Maryland, College Park, MD.
Brooks, M. Bioanalytical Chemistry Laboratory Manual, 2009, McGraw-Hill publishing, New York, NY
Mac, M.; Writing abstracts provides general chemistry students with an introduction to scientific writing; Chem. Educator, 11, 1-4.

Emily English, Ph.D.

To Emily English chemistry is a hobby and a profession. As an undergraduate at UM she showed enormous promise, a promise that has been realized. She has experience in organic synthesis and in protein chemistry. Her fondest wish is to see her love of chemistry develop in the students she teaches.

2007: Ph.D. Chemistry University of Wisconsin, Madison, WI
2002: B.S. Magna Cum Laude with Honors in Chemistry University of Maryland, College Park, MD

2006: Leah Cohodas Berk Award for Excellence in Chemistry Research, Department of Chemistry, University of Wisconsin, Madison
2006: Travel award - International Conference on Antiviral Research, San Juan, Puerto Rico
2005: McElvain Travel Award – Department of Chemistry, University of Wisconsin - Madison
2005-2006: NIH Chemistry and Biology Interface Traineeship, University of Wisconsin, Madison
2001: Goldwater Scholarship
2001: Phi Beta Kappa
2000-2002: Howard Hughes Medical Institute Undergraduate Research Fellowship

Technical Skills
Organic synthesis, small molecule purification, solid-phase peptide synthesis, HPLC purification of peptides and small molecules, NMR characterization of small molecules and peptides, tissue culture, cell-based assay development, protein expression

Akkarawongsa, R.; Potocky, T. B.; English, E. P.; Gellman, S. H.; Brandt, C. R. Inhibition of Herpes Simplex Virus Type 1 Infection by Cationic b-Peptides, Antimicrob. Agents Chemother. 2008, 52, 2120-2129.
Chi, Y.; English, E. P.; Pomerantz, W. C.; Horne, S. H.; Joyce, L. A.; Alexander, L. R.; Fleming, W. S.; Hopkins, E. A.; Gellman, S. H. Practical Synthesis of Enantiomerically Pure β2-Amino Acids via Proline-Catalyzed Diastereoselective Aminomethylation of Aldehydes, J. Am. Chem. Soc. 2007, 129, 6050-6055.
English, E. P.; Chumanov, R. S.; Gellman, S. H.; Compton, T. Rational Development of β-Peptide Inhibitors of Human Cytomegalovirus Entry, J. Biol. Chem. 2006, 281, 2661-2667.
Peelen, T. J.; Chi, Y.; English, E. P.; Gellman, S. H. Synthesis of 4,4-Disubstituted 2-Aminocyclopentanecarboxylic Acid Derivatives and Their Incorporation into 12-Helical β-Peptides. Org. Lett. 2004, 6, 4411-4414.
Dupont, J.; Bemish, R. J; McCarthy, K. E.; Payne, E. R.; Pollard, E. B.; Ripin, D. H. B.; Vanderplas, B. C.; Watrous, R. M. Oxidation of carbamate-protected alkylhydrazines to the corresponding hydrazones under Swern conditions. Tetrahedron Lett. 2001, 42, 5587.

"Concise Beta2-Amino Acid Synthesis Via Organocatalytic Aminomethylation" Chi, Y.; Gellman, S. H.; Pomerantz, W. C.; Horne, W. S.; Guo, L.; English, E. P. US Patent Pending.
"Beta-Polypeptides That Inhibit Cytomegalovirus Infection" Compton, T.; Gellman, S. H.; English, E. P.; Chumanov, R. S. U.S. Patent P05279US.

Robert Hall, Ph.D

Bob Hall is a microbiologist who has focused his research on infectious diseases and the pathogenic mechanisms in cholera, Salmonella, and enterohemorrhagic Escherichia coli. These studies have led to numerous research publications and presentations. Since 2002 he has been responsible for the extramural research program in cholera, other vibrio infections, and diagnostics for enteric and hepatic diseases at the National Institute for Allergy and Infectious Diseases. He has taught an expanded version of his course on Emerging Infectious Diseases in the Foundation for Advanced Education in the Sciences, the Graduate School at the National Institutes of Health in Bethesda, Maryland. Bob also teaches Microbiology in the University of Maryland Masters of Chemical and Life Sciences program, focusing on the physiological, ecological and industrial aspects of bacteria, viruses, fungi, and protists. In addition, Bob enjoys mentoring the Scholarly Papers of students, and has successfully seen over 40 students fulfill their Capstone thesis requirements.

1976-80: University of Aberdeen, Scotland, U.K. B.Sc. in Microbiology (1980).
1980-84: University of London, University College, England, U.K. Ph.D. in Microbiology (1984).
Employment History & Professional Experience
1983-85: Postdoctoral Research Fellow of the Wellcome Trust.
Department of Medical Microbiology, London School of Hygiene and Tropical Medicine, London, England, U.K.
1985-88: Postdoctoral Fellow of the Swiss Serum and Vaccine Inst. & NIAID
Center for Vaccine Development, University of Maryland, School of Medicine, Baltimore, MD.
1988-90: Instructor of Medicine
Center for Vaccine Development, University of Maryland, School of Medicine, Baltimore, MD.
1990-91: Research Assistant Professor (Medicine and Biological Chemistry)
Department of Biological Chemistry, University of Maryland, School of Medicine, Baltimore, MD.
1991-97: Senior Staff Fellow
Food and Drug Administration, Center for Food Safety and Applied Nutrition, Division of Virulence Assessment, Washington DC.
1997-2002: Microbiologist: Food and Drug Administration
Center for Food Safety & Applied Nutrition, Washington DC.
2002-present: Program Officer
National Institutes of Health, National Institute for Allergy & Infectious Disease, Division of Microbiology and Infectious Disease.

William Higgins, Ph.D.

BSCI 440, Mammalian Physiology; BSCI 207, Organismal Biology; BIOL 701, Teaching Biology

Graduate Program Affiliations
Master of Chemical & Life Sciences Online

Research Interests
Neuromodulation; opiate receptors; intercellular communication among unicellular organisms.

Current Research
Neuromodulation; opiate receptors; intercellular communication among unicellular organisms. Current activities focus on teaching and learning strategies.

Faculty Excellence Award for Teaching, College of Chemical and Life Sciences, 2006
William E. Kirwan Award for Excellence in Undergraduate Education, University of Maryland, College Park, 2005
Outstanding Faculty Advisor, Kappa Delta, Pan Hellenic Association, 1997 & 2003
Office of Multicultural Education Adviser/Mentor of the year Award, 2000
Outstanding Faculty Adviser, Maryland Panhellenic Association, 1997
Pan Hellenic Teacher of the Year Award; 1994
Outstanding Academic Advisor, Division of Agriculture & Life Sciences; 1984
Division of Agriculture & Life Sciences Faculty Excellence Award, Advising and Teaching; 1983
Student Government Association Excellence in Teaching Award, 1976

B.S. Biology, Boston College, 1969 Ph.D., Florida State University, 1973.

Dr. Lucinda Jack, Ph.D.

B.S. (Microbiology) University College, University of London, 1982
Ph.D. (Molecular Biology) University of London, 1986.

Courses Taught
BSCI 222 Principles of Genetics
CLFS 609A Food Safety and Genetically Modified Foods

Professional Experience
1/02 - present: Editing, Journal of Biological Chemistry , American Society of Biochemistry and Molecular Biology
7/99 - present: University Lecturer, College of Chemical and Life Sciences, University of Maryland, College Park, MD 20742.
7/97 - 6/99: Director of Science Outreach & Special Programs, College of Life Sciences, University of Maryland, College Park, MD 20742.
6/95 – 6/97: Assistant to the Dean, Science Outreach, College of Life Sciences, University of Maryland, College Park, MD 20742.
11/93 – 5/95: Manager of the Protein Sequencing Lab, Medical Biotechnology Center, University of Maryland at Baltimore.
6/90 – 9/93: Research Biologist, Agricultural Research Service, USDA, Beltsville, MD 20705.
10/86 – 6/90: Faculty Research Associate, Department of Animal Sciences, University of Maryland, College Park, MD 20742.
9/82 – 9/86: Medical Laboratory Scientific Officer, Courtauld Institute of Biochemistry, UCL and Middlesex Hospital School of Medicine, University of London, England.SCIENTIFIC

Genetics & Biochemistry: Cloning and characterizing genes encoding proteins expressed in milk; regulation and expression of transfected genes; ontogeny of expression of mammary gland development genes; the role of butyrophilin in milk-fat secretion; characterization of bacteriocidal and bacteriostatic bovine proteins; purification (HPLC) and characterization (sequencing) of proteins.
Food Safety: Transmissible spongiform encephalopathies, in vitro genetically-modified foods.
Selected Peer Reviewed Publications
Laird, J.E., Jack L.J.W., Hall, L., Boulton, A.P., Parker, D. and Craig, R.K. (1988). Structure and expression of the guinea-pig _-lactalbumin gene. Biochem. J. 254, 85 – 94.
Jack, L.J.W., and Mather, I.H. (1990). Molecular cloning and analysis of cDNA encoding bovine butyrophilin, an apical membrane glycoprotein expressed in lactating mammary tissue and secreted in association with the milk-fat globule membrane during lactation, J. Biol. Chem. 265, 14481 – 14486.
Madara, P.J., Banghart, L.R., Jack, L.J.W. and Mather, I.H. (1990). Affinity purification of polyclonal antibodies from antigen immobilized in situ in sodium dodecyl sulfate polyacrylamide gels. Anal. Biochem. 187, 246 – 250.
Mather, I.H. and Jack, L.J.W. (1993). A review of the molecular and cellular biology of butyrophilin, the major protein of bovine milk-fat globule membrane. J. Dairy Sci. 76,3832 – 3850.
Vernet, C., Boretto, J., Mattei, M-G., Takahashi, M., Jack, L.J.W., Mather, I.H., Rouquier, S., and Pontarotti, P. (1993). Evolutionary study of multigene families mapping close to the human MHC class I region. J. Mol. Evol. 37, 600 - 612.
Capuco A.V., Mein, G.A., Nickerson, S.C., Jack, L.J.W., Wood, D.L., Bright, S.A., Aschenbrenner, R.A., Miller, R.H., and Bitman, J. (1994). Influence of pulsationless milking on teat canal keratin and mastitis. J. Dairy Sci. 77, 64 – 74.
Jack, L.J.W., Kahl, S., St. Germain, D., and Capuco, A.V. (1994). Tissue distribution and regulation of 5'-deiodinase processes in lactating rats. J. Endocrinol. 142, 205 – 215.
Molenaar, A.J., Davis S.R., Jack L.J.W., and Wilkins, J. (1995). Expression of the butyrophilin gene, a milk–fat globule membrane protein, is associated with the expression of _-S1-casein gene. Histochem. J. 27, 388 – 394.
Banghart, L.R., Chamberlain, C.W., Velarde, J., Korobko, I.V., Ogg, S.L., Jack, L.J., Vakharia, V.N., and Mather. I.H. (1998). Butyrophilin is expressed in mammary epithelial cells from a single-sized messenger RNA as a type I membrane glycoprotein. J. Biol. Chem. 273, 4171 – 4179.
Mather I.H., Jack, L.J.W., Madara, P.J., and Johnson, V.G. (2001). The distribution of MUC1, an apical glycoprotein, in mammary epithelial cells at the resolution of the electron microscope: Implications for the mechanism of milk secretion. Cell Tiss. Res. 304, 91 – 101.

Bruce Jarvis, Ph.D., Professor Emeritus

B.S. Ohio Wesleyan University, 1963
Ph.D. University of Colorado, 1966

Research Interests
Isolation of Anti-Tumor Agents from Natural Sources, Chemistry of Indoor Air Molds, Medicinal Plant Chemistry, Mechanistic Studies in Bio-Organic Chemistry, Chemical Basis of Plant-Fungus Interactions.

Major Recognitions and Honors
Fellow, American Association for the Advancement of Science, 1989
Distinguished University Scholar/Teacher, 1991

Dr. David Jollie, Ph.D.

David Jollie taught biochemistry at the University of Maryland for six years. He was a most sought after teacher in those courses by students who responded to his love of the subject and his excellent presentations. His present course in the MCLFS program largely reflects his research interests in enzymology and the mechanisms of metalloprotein interaction and protein structure. David presently holds a position as a Program Manager at the National Institutes of Health.

University of Illinois, Urbana B.S. 1982
University of Minnesota, Minneapolis Ph.D. 1992
University of Southern California Postdoc 1992-1996
University of Maryland, Assistant Professor 1996-
NIH Pre-doctoral Fellowship 1987-1990
Graduate School Doctoral Dissertation Fellowship 1990-1991

Research Interests
Mechanisms of enzymes involved in anaerobic aromatic metabolism
Mechanisms of metalloproteins required for novel chemistry
Relationship of protein structure to redox potential in metallocenters

Dr. John Kapp, Ph.D.

John Kapp has held a number of teaching positions and has been recognized for his excellence as a teacher. He presently teaches CLFS 640 Human Physiology in the MCLFS program with his friend and colleague Bill Higgins. At he same time he leads the University of Maryland's Biological Sciences program at the budding Shady Grove campus

University of Maryland
Bachelor of Science, 1970
Major: Zoology
University of Maryland
Master of Science, 1974
Major: Physiology
Minor: Computer Science
University of Maryland
Ph.D., 1977
Major: Endocrinology
Academic Activities
Academic Awards and Honors
Phi Beta Kappa
Phi Kappa Phi
Graduated with High Honors
Panhellenic Association Outstanding Teacher Award, November 1994, University of Maryland, College Park

Experience in Higher Education
2001-2007: Program Director, Biological Sciences Degree Program at Shady Grove Center, College of Life Sciences, University of Maryland, College Park, Maryland
1999- 2001: Laboratory Coordinator and Lecturer, Department of Biological Sciences, University of Maryland, College Park, Maryland.
1990-1999: Visiting Assistant Professor and Lecturer, Department of Zoology
1983-1987: University of Maryland, College Park, Maryland.
1979-1981: Assistant Professor of Biology, Department of Biological Sciences, Salisbury State University, Salisbury, Maryland.
1978-1979: Instructor, Department of Biological Sciences, Salisbury State University, Salisbury, Maryland.
1976-1977: Instructor, Department of Biology, Montgomery College, Takoma Park, Maryland.

Bretton K. Kent, Ph.D.
Director of Undergraduate Studies, Department of Entomology
Director, Master of Life Sciences Program

Research Interests
Recent publications reflect my research interests. Two papers published in the paleontological journal, Mosasaur, concern the reconstructed paleobiology of a large, extinct lamnoid shark (Parotodus benedeni) based on an assemblage of 114 associated teeth from North Carolina. This assemblage is more than twice as large as any of the other three known for this species and the first from the Atlantic. Also published are two chapters in a monograph on a unique fossil assemblage from the Early Eocene of Virginia. The horizon is unusual in that it contains a rich, uncontaminated association of species, with a total of 32 shark and 18 ray species. I have recently discovered a second, slightly older and more offshore horizon from this site. Like the first horizon, this bed is uncontaminated, lying unconformably between two thick unfossiliferous layers of sediment. My current research is on reconstructing the feeding behavior of extinct sharks using a biomechanical model of tooth function.
As the departmental Director of Undergraduate Studies, I am responsible for producing the departmental portions of the Schedule of Classes each semester and the Undergraduate Catalog each year and coordinating the use of departmental resources for teaching and advising.
As Associate Director of the MCLFS Program Iam responsible for correlating mentor student relationships for the Scholarly Paper capstone experience as well as a number of other administrative tasks.

Oregon State University, B.S., magna cum laude, 1973
Oregon State University, M.S., 1976
University of Maryland, Ph.D., 1981

Representative Publications
Kent, B. W. 1983. Diet expansion of Busycon contrarium in the absence of Triplofusus giganteus. Nautilus 97: 103-104.
Kent, B. W. 1983. Natural history observations on the whelks Busycon contrarium (Conrad) and Busycotypus spiratum (Lamarck). J. Moll. Stud. 49:37-42.
Kent, B. W. 1987. Fossil Sharks of Maryland: An Illustrated Guide. Glossopetrae Press, Takoma Park, MD, 52 pp.
Kent, B. W. 1992. Making Dead Oysters Talk: Techniques for Analyzing Oysters from Archaeological Sites (2nd edition). Maryland Historical and Cultural Publ., Crownsville, MD, 76 pp.
Kent, B. W. 1994. Fossil Sharks of the Chesapeake Bay Region. Egan Rees and Boyer, Inc., Columbia, MD, 146 pp.
Kent, B. W. 1996. Biology of Extinct Animals Laboratory Manual. Campus Reprographics, College Park, MD, 162 pp.
Kent, B. W. and G. W. Powell, Jr. 1998. Reconstructed dentition of the rare lamnoid shark Parotodus benedeni (le Hon) from the Yorktown Formation (Early Pliocene) at Lee Creek Mine, North Carolina. Mosasaur 6: 1-10.
Kent, B. W. 1998. Speculations on the size and morphology of the extinct lamnoid shark,Parotodus benedeni (le Hon). Mosasaur 6: 11- 15.
Kent, B. W. 1999. Part 2 - Sharks from the Fisher/Sullivan Site. In: R. E. Weems (ed.). Fossil Vertebrates and Plants from the Fisher/Sullivan Site (Stafford County): A Record of Early Eocene Life in Virginia. Virginia Division of Mineral Resources, Publ. 152, pp. 11-37.
Kent, B. W. 1999. Part 3 - Rays from the Fisher/Sullivan Site. In: R. E. Weems (ed.). Fossil Vertebrates and Plants from the Fisher/Sullivan Site (Stafford County): A Record of Early Eocene Life in Virginia. Virginia Division of Mineral Resources, Publ. 152, pp. 39-51.

Awards and Recognition
UMCP College of Life Sciences Faculty Excellence Award for Teaching/Advising, 1993
UMCP Presidential Award for Outstanding Service to the Schools, 1994
UMCP Outstanding Faculty Author, October, 1994
Maryland Governor's Citation, 1995
American Fossil Federation Certificate of Appreciation, 1995

BSCI 105: Principles of Biology I
BSCI 106: Principles of Biology II
HONR 298W: Biology and Cultural History of Trout
BSCI 392: Biology of Extinct Animals
BSCI 393: Biology of Extinct Animals Laboratory
BIOL 488: Environmental Biology Institute
BIOL 489: Summer Biology Institute
CLFS 510: Concepts in Modern Biology
CLFS 710: Experimental Biology
CLFS 725: Statistics and Experimental Design

Dorothy Mazzocchi, Ph.D.

Dorothy Mazzocchi began teaching organic chemistry at the University of Maryland in 1976. In 1982 she entered the graduate school and earned her doctorate in 1987. For two years she taught both general and organic chemistry at Prince George's Community College and in 1989 returned to the University of Maryland as an instructor and the coordinator of the sophomore organic chemistry laboratories. Until her retirement in June 2000, she developed the organic lab program, wrote lab manuals supervised and instructed teaching assistants and lectured organic chemistry. She is proud of her participation on the design team for the state-of-the-art organic teaching labs in the new chemistry wing at the University of Maryland.

B.S. Chemistry, Queens College, Flushing, New York, 1960
M.A. Organic Chemistry, Queens College, City University of New York, Flushing, New York, 1964
Ph.D. Natural Product Organic Chemistry, University of Maryland, College Park, Maryland, 1987

Excellence in Teaching Award, University of Maryland, 1996
Curriculum and Course Development Award, College of Life Sciences, University of Maryland, 2000.

1989-2000: University of Maryland, College Park, Department of Chemistry, Instructor and Organic Chemistry Lab Coordinator.
1987-1989: Prince George's Community College, Physical Sciences Department, Associate Professor.
1979-1982: University of Maryland, College Park, Department of Chemistry, Instructor and Organic Chemistry Lab Coordinator.
1976-1979: University of Maryland, College Park, Department of Chemistry, Lecturer.
1963-1965: Queens College, City University of New York, Department of Chemistry, Lecturer.

Paul Mazzocchi, Ph.D.

Paul Mazzocchi has been in leadership positions at the University of Maryland throughout his career. He is well known for his ability and interest in starting new programs and shepherding them to the point of stability. Examples include his efforts as the founding leader of the University of Maryland Biotechnology Institute, the College of Chemical and Life Sciences, JIFSAN and his newest venture in launching the University of Maryland¹s first on line degree program, the Master of Chemical and Life Sciences (MCLFS) program. He teaches CLFS 680, Chemical Ecology with his best friend and colleague, Bruce Jarvis as well as CLFS 619A Molecular Spectroscopy.

B.S. Queens College of the City, University of New York, 1961
Ph.D. Fordham University, 1966

1965-1967: National Institutes Health postdoctoral fellow at Cornell University
1967: Assistant Professor of Chemistry, University of Maryland
1977: Professor, University of Maryland
1979-82: Associate Chair of the Chemistry Department
1982-89: Chair, the Department of Chemistry and Biochemistry
1985: Acting President (Director) of the University of Maryland Biotechnology Institute
1986-1989: Provost (Deputy Director), University of Maryland Biotechnology Institute
1989-92: Acting Dean of the College of Agriculture
1989-2000: Dean of the College of Life Sciences
1996-98: Acting Director, Joint Institute for Food Safety and Applied Nutrition (JIFSAN)
1998- : Associate Director, Joint Institute for Food Safety and Applied Nutrition (JIFSAN)
2000- : Director, Master of Chemical and Life Sciences Program
2002- : Professor Emeritus

Research Interests
Synthetic and Mechanistic Photochemistry, Science Education

Janet Norcross, Ph.D.

A.B. (Biology/German) - Lafayette College
M.A. (Biology - emphasis in Behavioral Ecology) - College of William and Mary
Ph.D. (Zoology-emphasis in Behavioral Endocrinology) - University of Maryland

Research Interests
Behavioral Endocrinology examining the mechanisms involved in the development of social, vocal and reproductive behavior in pair-bonding species.
My research has explored the hormonal bases of behavior using a pair-bonding nonhuman primate, the common marmoset, as a model. In this species, offspring remain with the parents and participate in the care of subsequent siblings well into their own adulthood. These helpers are reproductively suppressed through a currently unidentified mechanism. Specifically, my research has investigated the temporal development of appropriate adult-like behavior, including territorial and vocal behavior, in these helpers when they are removed from their family groups and paired with an unfamiliar potential mate. Further, to investigate mechanisms that may lead to reproductive behavior and the formation of pair bonds, I have investigated the behavioral, adrenal and gonadal responses of individuals to separation from familiar conspecifics using different social separation paradigms.

Recent Publications
Norcross, J.L, Newman, J.D. & L.M. Cofrancesco. 1999. Sex and context differences exist in the acoustic structure of phee calls by newly-paired common marmosets (Callithrix jacchus). Am. J. Primat., 49:165-181
Norcross, J.L. & J.D. Newman. 1999. Effects of separation and novelty on distress vocalizations and cortisol in the common marmoset (Callithrix jacchus). Am. J. Primat., 47:209-222
Norcross, J.L. & J.D. Newman. 1998. Gender is represented in phee calls produced by prepubertal common marmosets (Callithrix jacchus). Am. J. Primat., 45(2):197-198.
Roberts, R.L., Norcross, J.L. & J.D. Newman. 1998. Effects of social housing on steroid levels in common marmosets. 2nd Annual Meeting of the Society for Behavioral Neuroendocrinology, Atlanta, GA. (abstract)
Norcross, J.L. & J.D. Newman. 1997. Social context affects phee call production by nonreproductive common marmosets (Callithrix jacchus). Am. J. Primat., 43:135-145
Norcross, J.L. & J.D. Newman. 1995. Exposure to unfamiliar conspecifics alters hormones and behavior in the common marmoset. Am. J. Primat., 36(2):146
Norcross, J.L., Newman, J.D. & W. Fitch. 1994. Responses to natural and synthetic phee calls by common marmosets (Callithrix jacchus). Am. J. Primat., 33:15-29

Carol Pontzer, Ph.D.

Dr. Pontzer's research has been in the area of interferons and immune responses. She taught immunology and pharmacology for many years in College of Chemical and Life Sciences until she decided to change career paths and took her present position as a research administrator. Her participation in the MCLFS program allows her to continue with one of her first loves, teaching.

1976 B.A., Magna Cum Laude Biology
Frostburg State College, Maryland
1985 Ph.D. Biology
Marquette University, Milwaukee, WI
Major Advisor: Dr. Peter Abramoff
(Dissertation: Cellular Immunoregulation of Acute Pulmonary Inflammation in Strain 2 and Strain 13 Guinea Pigs.)
Postdoctoral Research Experience
1985-1989 Postdoctoral Associate, Department of Pathology, University of Florida, Gainesville, Florida, Advisor, Dr. Steve Russell
1989-1992 Postdoctoral Associate, Department of Microbiology and Cell Science University of Florida, Gainesville, Florida, Advisor, Dr. Howard M. Johnson

Professional Experience
1992-1993 Research Scientist, PepTech, Inc., Alachua, Florida Supervisors, Dr. Howard M. Johnson and Dr. C.P. Liu
1993-2002 Assistant Professor, Department of Cell Biology and Molecular Genetics University of Maryland, College Park, MD
2002-present Instructor, MCLFS Program and Science in the Evening Program University of Maryland, College Park, MD

Organization memberships
American Association of Immunologists, 1992-present
Sigma Xi, 1983-present
Society for Leukocyte Biology, 1984-present
International Society for Interferon Research, 1990-present
NIH Cytokine Interest Group, 1996-present
International Society for Antiviral Research, 1999-present

Tammatha O'Brien, Ph.D.

Tammatha O'Brien's current interest is in science education and course development. Most of the courses she teaches have an emphasis on human genetics and human physiology. Current literature is always incorporated into the courses she teaches to keep the material modern and relevant. As a lecturer she mentors students and has independent study projects to improve the undergraduate lab experience in biology courses.

Teaching Experience
University of Maryland
Genetics (BSCI222)
The World of Biology (BSCI103)
Endocrinology (BSCI447)
Anatomy and Physiology I (BSCI201)
Anatomy and Physiology II (BSCI202)
Biology of Reproduction (BSCI342)
Undergraduate Teaching Fellows Professional Development Seminar (BSCI279P)
College Park Scholars Colloquium: Biology, TV, and Movies (CPSP218L)
College Park Scholars Colloquium: Poisonous and Medicinal Plants (CPSP218L)
Endocrinology (CLFS609I)
The George Washington University School of Medicine and Health Sciences
Doctorate Program in Physical Therapy: Program Human Physiology
Prince George's Community College
Biology for Non-Majors, Cell Biology and Physiology, Genetics
Trinity University
Human Genetics for Nursing Students
Montgomery College
Biology for Non-Majors
Current Research and Interests
Science education and course development.

Recent Publications
Sibao Wang∗, Tammatha R. O'Brien∗, Monica Pava-Ripoll, Raymond J. St. Leger "Local adaptation of an introduced transgenic insect fungal pathogen due to new beneficial mutations", PNAS: submitted and accepted 11/2011
Race, Genomics, and Human Evolutionary History Lab Manual BSCI189I for the University of Maryland at College Park.
It's a Jungle Out There (Dec 2007) article for the magazine Groundwork: Publication of Landscape Contractors Association of MD-DC-VA
The World of Biology, Biology for Non-majors BSCI103 Lab Manual for the University of Maryland at College Park, Editions #1-4. Published by Hayden McNeil
Principles of Biology I; Biology for Majors BSCI105. Lab Manual for the University of Maryland at College Park. Published by Hayden McNeil.
Cell Biology and Physiology (BSCI330) Lab Manual for the University of Maryland at Shady Grove.

Allen L. Steinhauer Award for Excellence in Teaching. Department of Entomology, University of Maryland 2006

2008: Ph.D. in Entomology with an emphasis in Molecular Genetics University of Maryland

Nancy Trun, Ph.D.

1982: B.S. Microbiology, Ohio State University
1988: Ph.D. Molecular Biology, Princeton University
1993: Post Doctorate, National Institutes of Health

Research Interests
Folding of chromosomes in bacteria and communicable diseases in feral cat populations.Chromosome Folding. Chromosomes are long very thin molecules that must be folded correctly in order to be functional and to fit inside of the cell. Using the model system E. coli, we have identified a family of small DNA binding proteins, called Csp proteins, which help fold the chromosome. E. coli K-12 encodes nine csp genes that are expressed at different times during cell growth. Some are induced by cold shock, some by nutritional deprivation, some by stationary phase and some are expressed throughout the growth curve. The cell requires the presence of Csp proteins for viability, however no individual Csp has been shown to be essential.

We are currently studying:
The biochemistry of CspE to determine what nucleic acid substrates it will bind to and what the requirements for binding are.
The phenotypes associated with overproduction of wild-type and mutant cspE genes to determine the role(s) it plays in vivo.
The consequences associated with deleting multiple csp genes.
Mutants in CspE that distinguish between its roles in gene regulation and the effects they have on DNA topography.

Feral cats
We have recently begun a project to look at the number and type of communicable disease carried by feral cats. It is estimated that there are approximately 100 million free-roaming and feral cats in the United States alone. These animals live in every setting you could possibly imagine yet very little is known about them. In conjunction with Dr. Lisa Ludvico, Dr. Becky Morrow, and a non-profit organization that employs the Trap-Neuter-Return approach to the animals, we are investigating the genetic relatedness of individual members of cat colonies, the health of each animal and the number and types of communicable diseases that they carry. We are comparing the data from feral populations to client-owned indoor cats.

Teaching Interests
I teach a variety of upper level microbiology related courses including traditional lecture courses and a semester-long in depth laboratory class. My interests lie in engaging the students in my class material so that they want to learn. I am currently piloting service-learning in the study of the feral cats. My lab course is full research project with each student conducting a part of the feral cat work. The students are also required to spend a given number of hours each semester with either the Trap-Neuter-Return non-profit or a local animal shelter we work with. These experiences are incorporated into the lab in the form of projects the students complete. These additions to a traditional lab allow the students to see first hand what the problem is and how they can help solve it.

Selected Publications
Hu, K., Liu, E. Dean, K. Gingras, M., DeGraff, W. and Trun , N.J. Overproduction of three genes leads to camphor resistance and chromosome condensation in E. coli. Genetics 143:1521-1532, 1996.
Trun, N.J. and Marko, J. The architecture of a functional chromosome. ASM News. 64 (5): 276-283, 1998.
Sand, O., Gingras, M., Beck, N., Hall, C., and Trun , N.J. The E. coli chromosome condensing proteins, CrcA, CspE and CrcB can partially substitute for mutations in topoisomerase IV, MukB, Fis, IHF, HU and HNS in vivo. Microbiology 149:2107-2117, 2003.
Trun, N.J. and Johnston, D. Folding chromosomes in bacteria: Examining the role of Csp proteins and other small nucleic acid-binding proteins. Current Topics in Develop. Biology 55:173-201, 2003.

Fundamental Bacterial Genetics. N. Trun and J. Trempy. Blackwell Publishing. Malden , MA . 2004.964 BS Utah State University- Biology/Secondary Education

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