Terp Young Scholars

July 12-31, 2020

ENGR-Maryland Technology Enterprise Institute

BIOE160: Biopharmaceutical Production

Online Instruction Details—Synchronous Instruction: 75%, Asynchronous Instruction: 25%

Note: In addition to the synchronous meeting times, this course also involves asynchronous material that students will need to access and complete on their own time.

Ever wonder how human insulin can be made from E.coli? Since the 1980s, biotech companies have been making medical drugs using biotechnology. These companies use living cells to produce proteins, antibodies, and nucleic acids for therapeutic purposes. This course takes students through a biotechnology “campaign” where they will transform E.coli into a green fluorescent protein factory. Students work in teams, simulating a start-up biotech company.  Teams will attempt to optimize expression of proteins, run industrial-sized fermentors, perform protein analysis and separations, and purify their own biopharmaceuticals, on time and under budget. This course focuses on the basics of recombinant DNA technology, as applied to biopharmaceutical manufacturing, in a classroom setting. Students will work through a “production campaign” including all key steps of manufacturing a protein product.

Course Prerequisite: Students must complete high school biology and chemistry before enrolling in this course.

Course Supplies: Students will need to purchase the BIOE160 course materials to participate in the course. (Once the supply list is ready it will be emailed to registered students).

Technical Requirements: The virtual classroom is a dynamic space, visit our Technical Requirements page to confirm you have the necessary technology to be successful in this online course.

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